Molecular testing for Aspergillus
Low sensitivity and slow time to result due to culture methods lead to poor clinical outcomes with traditional methods. Implementing rapid, culture free diagnostic PCR methods improves patient outcomes.
The Fungiplex® Aspergillus IVD PCR Kit is a real-time PCR designed to detect the main species associated with IA, and differentiates species resistant to first-line treatment:
- Aspergillus spp. (A. fumigatus, A. flavus, A. niger)
- A. terreus.
The Fungiplex® Aspergillus IVD PCR Kit provides results in under 2 hours from extracted DNA, helping the laboratory support clinical decision-making when time matters.
The inclusion of real-time PCR in regular biomarker testing strategies for the diagnosis of IA can reduce the time to diagnosis, reduce the use of empiric therapy and ultimately, reduce the cost of care.
The Fungiplex® Aspergillus IVD PCR Kit is suitable for the routine testing of patients at risk of IA, and is compatible with samples taken for other biomarker tests:
- Validated on DNA extracted from whole blood, serum, plasma
- Validated on DNA extracted from bronchoalveolar lavage (BAL) fluid.
The Fungiplex® Aspergillus IVD PCR Kit is provided in an easy to use master-mix format and is designed to run on existing laboratory equipment, minimizing the need for dedicated bench space or additional training:
- ABI 7500
- ABI QuantStudio 5
- Bio-Rad CFX
- Hain FluoroCycler® XT
- Mic qPCR Cycler
- Roche Lightcycler 480 II
- Qiagen RotorGene.